Pimecrolimus kremin (%1) atopik dermatit tedavisindeki etkinliği

Pimecrolimus 1% cream (Elidel) for atopic dermatitis.

Pimecrolimus is an immunomodulating medication that inhibits production of inflammatory cytokines in the skin and this compound was specifically developed for the treatment of inflammatory skin diseases. Phase II and III clinical trials with the topical formulation of pimecrolimus (Elidel cream, Novartis) have shown that it is safe and effective for use in patients with atopic dermatitis (AD). ...

Treatment of oral lichen sclerosus with 1% pimecrolimus cream.

Lichen sclerosus is a chronic inflammatory mucocutaneous disorder predominately affecting prepubertal girls and postmenopausal women. Isolated lichen sclerosus affecting the oral mucosa is exceedingly rare, and only 13 patients with biopsy-proved isolated oral disease have been reported in the literature. We report on a 7-year-old Korean girl with a well-demarcated 1.2x1.2 cm atrophic white pla...

Pimecrolimus 1% cream for anogenital lichen sclerosus in childhood

BACKGROUND Lichen sclerosus is a chronic inflammatory disease with a predilection of the anogenital region. Because of the potential side effects of repeated local application of potent glucocorticosteroids, equally-effective, safer therapeutic options are required, especially in the treatment of children. CASE PRESENTATIONS We report on the efficacy of twice-daily application of pimecrolimus...

Pimecrolimus for the treatment of atopic dermatitis

Treatment of oral erosive lichen planus with 1% pimecrolimus cream: a double-blind, randomized, prospective trial with measurement of pimecrolimus levels in the blood.

OBJECTIVES To evaluate the efficacy of 1% pimecrolimus cream in treating oral erosive lichen planus and to assess its tolerance. DESIGN Double-blind randomized trial with placebo control. SETTING Outpatients of the Department of Dermatology, University Hospital of Nice, from December 21, 2004, to April 19, 2005. PATIENTS Fourteen consecutive patients with oral erosive lichen planus confir...